BDBM667112 7-(5-chloro-2-fluorophenyl)-1-{1H- pyrazolo[3,4- b]pyridin-4-yl}-1H,2H,3H- pyrido[3,4-b][1,4]oxazine::US20240116947, Example 15

SMILES Fc1ccc(Cl)cc1-c1cc2N(CCOc2cn1)c1ccnc2[nH]ncc12

InChI Key InChIKey=HSWUFDGDPIWKHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667112   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM667112(US20240116947, Example 15 | 7-(5-chloro-2-fluoroph...)
Affinity DataIC50: 3nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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