BDBM666469 US20240116946, Example 502

SMILES COc1ccc(Cl)c(c1)-c1cc2[nH]c(=O)n(-c3cncc4cn(CC(F)(F)F)nc34)c(=O)c2s1

InChI Key InChIKey=XDKRLUHUMUCQTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 666469   

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666469(US20240116946, Example 502)
Affinity DataIC50: 2.54nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent