BDBM666161 US20240116946, Example 194

SMILES Clc1cccc(-c2cccc3C(=O)NCCc23)c1-c1ccc2c(c1)[nH]c(=O)n(-c1cncc3ccccc13)c2=O

InChI Key InChIKey=PIHBIKYRUIIZJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 666161   

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666161(US20240116946, Example 194)
Affinity DataIC50: 2.54nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent