BDBM665966 1-(3-{4-[4-(trifluoromethyl)phenyl]-2- quinazolinyl}-1-pyrrolidinyl)-2-propen-1-one::US20240116926, Comparative Example C

SMILES FC(F)(F)c1ccc(cc1)-c1nc(nc2ccccc12)[C@@H]1CCN(C1)C(=O)C=C

InChI Key InChIKey=XXCDFBZEAJGPSZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665966   

TargetTranscriptional enhancer factor TEF-3 [217-434](Human)
Astrazeneca

US Patent
LigandPNGBDBM665966(US20240116926, Comparative Example C | 1-(3-{4-[4-...)
Affinity DataIC50: 55nMAssay Description:Compound IC50 values were assessed following a 10-point, half-log10 dilution schema starting at 100 μM compound concentration. Specifically, hum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
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