BDBM665902 US20240116922, Comparator 5A

SMILES CC(C)Oc1nc2nc(cn2cc1C(=O)Nc1cccc(n1)C(F)F)C12CCC(C)(CC1)OC2

InChI Key InChIKey=PWAPLCQWBOAZGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665902   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM665902(US20240116922, Comparator 5A)
Affinity DataIC50: 0.100nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent