BDBM665883 US20240116922, Example 185

SMILES C[C@@H](Oc1cc2nc(cn2cc1C(=O)Nc1cccn(C2C[C@H]2F)c1=O)C12CC(C)(C1)OC2)C(F)F

InChI Key InChIKey=KMPNCUHEWYNYLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665883   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM665883(US20240116922, Example 185)
Affinity DataIC50: 0.100nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent