BDBM665873 US20240116922, Example 175

SMILES CC12CC(C1)(CO2)c1cn2cc(C(=O)Nc3cccn(C4C[C@H]4F)c3=O)c(OC3CC3)cc2n1

InChI Key InChIKey=CWULTDUDCASWIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665873   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM665873(US20240116922, Example 175)
Affinity DataIC50: 0.200nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent