BDBM665834 US20240116922, Example 136

SMILES CC(C)Oc1nc2nc(cn2cc1C(=O)Nc1cccn([C@H]2C[C@H]2C)c1=O)C12CC(C)(C1)OC2

InChI Key InChIKey=PWTPYKWGULDCHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 665834   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM665834(US20240116922, Example 136)
Affinity DataIC50: 4nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM665834(US20240116922, Example 136)
Affinity DataIC50: 0.560nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed