BDBM665794 US20240116922, Example 96

SMILES CC[C@H](C)Oc1cc2nc(cn2cc1C(=O)Nc1cccn([C@@H]2C[C@@H]2F)c1=O)C12CC(C)(C1)OC2

InChI Key InChIKey=QAQYGSGLVMWMNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665794   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM665794(US20240116922, Example 96)
Affinity DataIC50: 0.200nMAssay Description:The 2-hour 1 mM ATP Biochemical Assay employed a MesoScale Detection (MSD) format. The kinase reaction was based on the IRAK4 phosphorylation of a bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent