BDBM665689 5-(6-((1R,3R,5S)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)pyridin-3-yl)-1,3,4-oxadiazol-2(3H)-one::US20240116912, Example 68

SMILES FC(F)(F)Oc1ccccc1-c1noc(C2CC2)c1CO[C@@H]1C[C@@H]2CC[C@H](C1)N2c1ccc(cn1)-c1n[nH]c(=O)o1

InChI Key InChIKey=YFLHDEJDOKGGSC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665689   

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665689(US20240116912, Example 68 | 5-(6-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  26.4nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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