BDBM665668 3-(4-(4-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methoxy)azepan-1-yl)phenyl)-1,2,4-oxadiazol-5(4H)-one::US20240116912, Example 47

SMILES FC(F)(F)Oc1ccccc1-c1noc(C2CC2)c1COC1CCCN(CC1)c1ccc(cc1)-c1noc(=O)[nH]1

InChI Key InChIKey=VLYBNKUTHOFPGK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665668   

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665668(US20240116912, Example 47 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  3.70nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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