BDBM665664 6-(6-(4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)pyridin-3-yl)-1,2,4-triazine-3, 5(2H,4H)-dione::US20240116912, Example 43

SMILES Clc1cccc(Cl)c1-c1noc(C2CC2)c1COC1CCN(CC1)c1ccc(cn1)-c1n[nH]c(=O)[nH]c1=O

InChI Key InChIKey=AMAUCSHHMGEUTN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665664   

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665664(US20240116912, Example 43 | 6-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  11.2nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent