BDBM665657 3-(4-(4-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)phenyl)-1,2,4-oxadiazol-5(4H)-one::US20240116912, Example 36

SMILES FC(F)(F)Oc1ccccc1-c1noc(C2CC2)c1COC1CCN(CC1)c1ccc(cc1)-c1noc(=O)[nH]1

InChI Key InChIKey=DPFJJVPFDCVGAN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665657   

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665657(US20240116912, Example 36 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  18.8nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent