BDBM665655 3-(4-((3R,4R)-4-((5-cyclopropyl-3- (2,6-dichlorophenyl)isoxazol-4- yl)methoxy)-3-methylpiperidin-1- yl)phenyl)-1,2,4-oxadiazol-5(4H)-one::US20240116912, Example 34

SMILES C[C@@H]1CN(CC[C@H]1OCc1c(onc1-c1c(Cl)cccc1Cl)C1CC1)c1ccc(cc1)-c1noc(=O)[nH]1

InChI Key InChIKey=VGLOGNKYXIRKHR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665655   

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665655(US20240116912, Example 34 | 3-(4-((3R,4R)-4-((5-cy...)
Affinity DataEC50:  153nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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