BDBM665634 3-(4-(4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-2-fluorophenyl)-1,2,4-oxadiazol-5(4H)-one::US20240116912, Example 13

SMILES Fc1cc(ccc1-c1noc(=O)[nH]1)N1CCC(CC1)OCc1c(onc1-c1c(Cl)cccc1Cl)C1CC1

InChI Key InChIKey=SZUTZPIRLJSLMT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665634   

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665634(US20240116912, Example 13 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  3.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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