BDBM664702 (2S)-1-(((1S,3R,5S)-3-hydroxyadamantan-1- yl)glycyl)pyrrolidine-2-carbonitrile (vildagliptin)::US20240115577, Compound 3

SMILES O[C@@]12CC3C[C@H](C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 664702   

TargetDipeptidyl peptidase 4(Human)
THE SCRIPPS RESEARCH INSTITUTE

US Patent
LigandPNGBDBM664702((2S)-1-(((1S,3R,5S)-3-hydroxyadamantan-1- yl)glycy...)
Affinity DataIC50: 4.80nMAssay Description:Human DPP4 activity assay data were obtained using a DPP4 Activity Assay Kit (Sigma-Aldrich, MAK088) according to the manufacturer's instructions...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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