BDBM664617 US20240109930, Example 1.2.37.::tert-butyl (4-(1-(((2R,3R,4S,5R,6R)-4-(4-(2,3-difluoro-4-methylphenyl)-1H- 1,2,3-triazol-1-yl)-5-hydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H- pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)bicyclo[2.2.2]octan-1-yl)carbamate

SMILES COC1=C(N2CC(NN2)c2ccc(C)c(F)c2F)C(O)=C(CO)O[C@@H]1Cn1cc(nn1)C12CCC(CC1)(CC2)NC(=O)OC(C)(C)C

InChI Key InChIKey=KNIFHSSZBWYSOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 664617   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664617(US20240109930, Example 1.2.37. | tert-butyl (4-(1-...)
Affinity DataIC50: 20nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664617(US20240109930, Example 1.2.37. | tert-butyl (4-(1-...)
Affinity DataIC50: 9.40E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent