BDBM664598 (2R,3R,4S,5R,6R)-4-(4-(4-chloro-2,3-difluorophenyl)-1H-1,2,3-triazol-1- yl)-6-((1-(1-(difluoromethyl)cyclopropyl)-1H-1,2,3-triazol-4-yl)methyl)-2- (hydroxymethyl)-5-methoxytetrahydro-2H-pyran-3-ol::US20240109930, Example 2.1.51.

SMILES CO[C@H]1[C@@H](Cc2cn(nn2)C2(CC2)C(F)F)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Cl)c(F)c1F

InChI Key InChIKey=HBQXIUJBNMAIKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 664598   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664598((2R,3R,4S,5R,6R)-4-(4-(4-chloro-2,3-difluorophenyl...)
Affinity DataIC50: 20nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664598((2R,3R,4S,5R,6R)-4-(4-(4-chloro-2,3-difluorophenyl...)
Affinity DataIC50: 830nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent