BDBM664428 (2R,3R,4S,5R,6R)-6-((1-(3,3-difluoro-1-methylcyclobutyl)-1H-1,2,3- triazol-4-yl)methyl)-4-(4-(2,3-difluoro-4-methylphenyl)-1H-1,2,3-triazol-1- yl)-2-(hydroxymethyl)-5-methoxytetrahydro-2H-pyran-3-ol::US20240109930, Example 1.1.15.

SMILES CO[C@H]1[C@@H](Cc2cn(nn2)C2(C)CC(F)(F)C2)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(C)c(F)c1F

InChI Key InChIKey=OCRKARTVUIJCHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 664428   

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664428(US20240109930, Example 1.1.15. | (2R,3R,4S,5R,6R)-...)
Affinity DataIC50: 1.76E+3nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM664428(US20240109930, Example 1.1.15. | (2R,3R,4S,5R,6R)-...)
Affinity DataIC50: 30nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384well plates are supplemented with 22.8 μL/well of biotinylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent