BDBM663805 US20240109912, Compound 139

SMILES CC#CC(=O)N1CC(C1)N1CCC(CC1)c1cc2Nc3ncnc(N4CCS(=O)(=O)CC4)c3[C@@H](C)Oc2c(C)n1

InChI Key InChIKey=WXMOXAQMFWVLEI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 663805   

TargetCyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM663805(US20240109912, Compound 139)
Affinity DataKi:  0.0470nMAssay Description:CDK7 activity is measured by following the production of ADP generated from ATP-dependent phosphorylation of the peptide substrate derived from RNA P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM663805(US20240109912, Compound 139)
Affinity DataKi:  0.135nMAssay Description:CDK7 activity is measured by following the production of ADP generated from ATP-dependent phosphorylation of the peptide substrate derived from RNA P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent