BDBM663779 US20240109912, Compound 110

SMILES Cc1cc(cc2Nc3ncnc(C4CCS(=N)(=O)CC4)c3COc12)C1CN(C1)C1CN(C1)C(=O)C=C

InChI Key InChIKey=KBEHQUCESIXJEW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663779   

TargetCyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM663779(US20240109912, Compound 110)
Affinity DataKi:  0.0320nMAssay Description:CDK7 activity is measured by following the production of ADP generated from ATP-dependent phosphorylation of the peptide substrate derived from RNA P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent