BDBM663715 US20240109912, Compound 32

SMILES C[C@@H]1Oc2c(C)cc(cc2Nc2ncnc(N3CCS(=O)(=O)CC3)c12)C1CCN(CC1)C1CN(C1)C(=O)C=C

InChI Key InChIKey=GEJQJTGWWUQEMM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663715   

TargetCyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM663715(US20240109912, Compound 32)
Affinity DataKi:  0.0250nMAssay Description:CDK7 activity is measured by following the production of ADP generated from ATP-dependent phosphorylation of the peptide substrate derived from RNA P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent