BDBM663203 ((1S,6R,7S)-3-(3-(5-fluoroquinolin-4-yl)-1H- pyrazolo[3,4-b]pyrazin-6-yl)-7-(5-methylisoxazol-3- yl)-3-azabicyclo[4.1.0]heptan-7-yl)methanamine::US20240109900, Example 41

SMILES Cc1cc(no1)[C@@]1(CN)[C@@H]2CCN(C[C@H]12)c1cnc2c(n[nH]c2n1)-c1ccnc2cccc(F)c12

InChI Key InChIKey=MIIWAJRVEHJIKN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663203   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
IRBM

US Patent

LigandBDBM663203(((1S,6R,7S)-3-(3-(5-fluoroquinolin-4-yl)-1H- pyraz...)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/20/2024
Entry Details
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