BDBM663202 ((1S,6R,7S)-3-(3-(2,3-dihydrobenzo[b][1,4]dioxin-5- yl)-1H-pyrazolo[3,4-b]pyrazin-6-yl)-7-(5- methylisoxazol-3-yl)-3-azabicyclo[4.1.0]heptan-7- yl)methanamine::US20240109900, Example 40

SMILES Cc1cc(no1)[C@@]1(CN)[C@@H]2CCN(C[C@H]12)c1cnc2c(n[nH]c2n1)-c1cccc2OCCOc12

InChI Key InChIKey=XYZNAUCSXZHZPP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663202   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
IRBM

US Patent

LigandBDBM663202(((1S,6R,7S)-3-(3-(2,3-dihydrobenzo[b][1,4]dioxin-5...)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/20/2024
Entry Details
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