BDBM663184 (3-(3-(8-methoxyquinolin-5-yl)-1H-pyrazolo[3,4- b]pyrazin-6-yl)-7-(5-methylisoxazol-3-yl)-3- azabicyclo[4.1.0]heptan-7-yl)methanamine::US20240109900, Example 22

SMILES COc1ccc(-c2n[nH]c3nc(cnc23)N2CCC3C(C2)C3(CN)c2cc(C)on2)c2cccnc12

InChI Key InChIKey=WQNCQRJTYAMFAQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663184   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
IRBM

US Patent

LigandBDBM663184((3-(3-(8-methoxyquinolin-5-yl)-1H-pyrazolo[3,4- b]...)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/20/2024
Entry Details
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