BDBM663176 (3-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4- b]pyrazin-6-yl)-7-(4-methylisoxazol-3-yl)-3- azabicyclo[4.1.0]heptan-7-yl)methanamine::US20240109900, Example 14

SMILES Cc1conc1C1(CN)C2CCN(CC12)c1cnc2c(n[nH]c2n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=HVHBFUCKIAPUIF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663176   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
IRBM

US Patent

LigandBDBM663176((3-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4- b]pyra...)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Assay volume of 20 μL/well was assembled in 384 well black polystyrene low-binding microplates (Greiner), using the following buffer: 60 mM HEPE...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/20/2024
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL