BDBM663078 US20240109898, Compound Z-5::US20240109898, Compound Z-5-1::US20240109898, Compound Z-5-2

SMILES CC(C1CC1)c1cc(N[C@H]2CC[C@H](N)C2)n2nccc2n1

InChI Key InChIKey=SZWIEOISRBXPJU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 663078   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663078(US20240109898, Compound Z-5 | US20240109898, Compo...)
Affinity DataIC50: 17nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663078(US20240109898, Compound Z-5 | US20240109898, Compo...)
Affinity DataIC50: 23nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663078(US20240109898, Compound Z-5 | US20240109898, Compo...)
Affinity DataIC50: 7nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663078(US20240109898, Compound Z-5 | US20240109898, Compo...)
Affinity DataIC50: 2.20E+3nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663078(US20240109898, Compound Z-5 | US20240109898, Compo...)
Affinity DataIC50: 3.99E+3nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663078(US20240109898, Compound Z-5 | US20240109898, Compo...)
Affinity DataIC50: 1.43E+3nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663078(US20240109898, Compound Z-5 | US20240109898, Compo...)
Affinity DataIC50: 9.13E+3nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663078(US20240109898, Compound Z-5 | US20240109898, Compo...)
Affinity DataIC50: 838nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663078(US20240109898, Compound Z-5 | US20240109898, Compo...)
Affinity DataIC50: 887nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent