BDBM663077 US20240109898, Compound Z-4

SMILES N[C@H]1CC[C@@H](C1)Nc1cc(nc2c(cnn12)C#N)C(C1CC1)C1CC1

InChI Key InChIKey=NEXNKMPOCOPVBN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 663077   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663077(US20240109898, Compound Z-4)
Affinity DataIC50: 14nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663077(US20240109898, Compound Z-4)
Affinity DataIC50: 716nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Shanghai Haiyan Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM663077(US20240109898, Compound Z-4)
Affinity DataIC50: 828nMAssay Description:The inhibiting effects on the kinase activity of CDK1/CycB (Carna bioscience, #04-102), CDK2/CycA (Carna bioscience, #04-103) and CDK9/CycT (Carna bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent