BDBM663033 Synthesis of N-(6-((1H-pyrazol-1-yl)methyl)-4-(fluoromethoxy)benzo[d] isoxazol-3-yl)-2,4-dimethoxypyridine-3-sulfonamide ::US20240109880, Compound 58::US20250122182, Compound 59, WO2023/088233

SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Oc3nccs3)cc(OCF)c12

InChI Key InChIKey=SOOLWFNFCBAOHR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 663033   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM663033(Synthesis of N-(6-((1H-pyrazol-1-yl)methyl)-4-(flu...)
Affinity DataIC50: 5nMAssay Description:Inhibition of KAT6A enzymatic activity by test compounds was determined using a radiometric 384-well format assay. A 10-point serial dilution of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
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TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandPNGBDBM663033(Synthesis of N-(6-((1H-pyrazol-1-yl)methyl)-4-(flu...)
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6B(Human)
Isosterix

US Patent
LigandPNGBDBM663033(Synthesis of N-(6-((1H-pyrazol-1-yl)methyl)-4-(flu...)
Affinity DataIC50: 25.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
Go to US Patent