BDBM663003 Synthesis of 2,4-dimethoxy-N-(5-(pyridin-2-yloxy)-3,4-dihydro-2H-chromeno[8,7-d]isoxazol-9-yl)pyridine-3-sulfonamide ::US20240109880, Compound 28

SMILES COc1ccnc(OC)c1S(=O)(=O)Nc1noc2cc(Oc3ccccn3)c3CCCOc3c12

InChI Key InChIKey=LUALHRITMFJPIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 663003   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM663003(Synthesis of 2,4-dimethoxy-N-(5-(pyridin-2-yloxy)-...)
Affinity DataIC50: 55nMAssay Description:Inhibition of KAT6A enzymatic activity by test compounds was determined using a radiometric 384-well format assay. A 10-point serial dilution of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent