BDBM662700 US20240109865, Example 123.::methyl 6-[5-[5-[(1R)-1- (3,5-dichloro-4- pyridyl)ethoxy]-1H- indazol-3-yl]-2-pyridyl]- 2,6-diazaspiro[3.3]heptane- 2-carboxylate

SMILES COC(=O)N1CC2(C1)CN(C2)c1ccc(cn1)-c1n[nH]c2ccc(O[C@H](C)c3c(Cl)cncc3Cl)cc12

InChI Key InChIKey=BVPBJTYNELJHDI-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 662700   

TargetFibroblast growth factor receptor 1(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662700(US20240109865, Example 123. | methyl 6-[5-[5-[(1R)...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662700(US20240109865, Example 123. | methyl 6-[5-[5-[(1R)...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662700(US20240109865, Example 123. | methyl 6-[5-[5-[(1R)...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3 [V555M](Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662700(US20240109865, Example 123. | methyl 6-[5-[5-[(1R)...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 4(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM662700(US20240109865, Example 123. | methyl 6-[5-[5-[(1R)...)
Affinity DataKd:  10nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent