BDBM662536 (S)-N-(4-(2-(4- chlorophenyl)-1- methoxypropan-2- yl)thiazol-2-yl)-2,6- difluoro-4-(piperazin- 1-yl)benzamide::US20240109853, Compound C025::US20240226094, Compound C025

SMILES COC[C@](C)(c1csc(NC(=O)c2c(F)cc(cc2F)N2CCNCC2)n1)c1ccc(Cl)cc1

InChI Key InChIKey=IEPJRSOJGFFOHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 662536   

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662536((S)-N-(4-(2-(4- chlorophenyl)-1- methoxypropan-2- ...)
Affinity DataIC50: 8nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662536((S)-N-(4-(2-(4- chlorophenyl)-1- methoxypropan-2- ...)
Affinity DataIC50: 8nMAssay Description:ALPK1 kinase activity was measured in an in vitro assay using ADP-Heptose as the ALPK1 ligand and activator of its kinase activity and TIFA protein a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent