BDBM662324 N-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol-2-yl)-3-(4- (piperazin-1- yl)phenyl)azetidine-1- carboxamide::US20240109853, Compound A237::US20240226094, Compound A237

SMILES CC(C#C)(c1csc(NC(=O)N2CC(C2)c2ccc(cc2)N2CCNCC2)n1)c1ccc(Br)cc1

InChI Key InChIKey=OATDIDMBBFFGOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 662324   

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662324(N-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol-2-y...)
Affinity DataIC50: 7nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662324(N-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol-2-y...)
Affinity DataIC50: 7nMAssay Description:ALPK1 kinase activity was measured in an in vitro assay using ADP-Heptose as the ALPK1 ligand and activator of its kinase activity and TIFA protein a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent