BDBM662300 1-(4-(2-(4- bromophenyl)propan-2- yl)thiazol-2-yl)-3-(4- (3,5-dimethylpiperazin- 1-yl)benzyl)urea::US20240109853, Compound A213::US20240226094, Compound A213

SMILES CC1CN(CC(C)N1)c1ccc(CNC(=O)Nc2nc(cs2)C(C)(C)c2ccc(Br)cc2)cc1

InChI Key InChIKey=ARNHZDBPMUAGDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 662300   

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662300(1-(4-(2-(4- bromophenyl)propan-2- yl)thiazol-2-yl)...)
Affinity DataIC50: 9nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662300(1-(4-(2-(4- bromophenyl)propan-2- yl)thiazol-2-yl)...)
Affinity DataIC50: 9nMAssay Description:ALPK1 kinase activity was measured in an in vitro assay using ADP-Heptose as the ALPK1 ligand and activator of its kinase activity and TIFA protein a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent