BDBM662280 1-(4-(4-aminopiperidin- 1-yl)benzyl)-3-(4-(1-(4- bromophenyl)cyclopent- yl)thiazol-2-yl)urea::US20240109853, Compound A193::US20240226094, Compound A193

SMILES NC1CCN(CC1)c1ncc(CNC(=O)Nc2nc(cs2)C2(CCCC2)c2ccc(Br)cc2)cn1

InChI Key InChIKey=NIKPHIOEUWMKKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 662280   

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662280(1-(4-(4-aminopiperidin- 1-yl)benzyl)-3-(4-(1-(4- b...)
Affinity DataIC50: 15nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662280(1-(4-(4-aminopiperidin- 1-yl)benzyl)-3-(4-(1-(4- b...)
Affinity DataIC50: 15nMAssay Description:ALPK1 kinase activity was measured in an in vitro assay using ADP-Heptose as the ALPK1 ligand and activator of its kinase activity and TIFA protein a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent