BDBM662254 (S)-N-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol-2-yl)-3- (hydroxymethyl)azetidine- 1-carboxamide::US20240109853, Compound A167::US20240226094, Compound A167

SMILES C[C@@](C#C)(c1csc(NC(=O)N2CC(CO)C2)n1)c1ccc(Br)cc1

InChI Key InChIKey=AUBUCWFNYBWRNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 662254   

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662254((S)-N-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol...)
Affinity DataIC50: 7nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandPNGBDBM662254((S)-N-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol...)
Affinity DataIC50: 7nMAssay Description:ALPK1 kinase activity was measured in an in vitro assay using ADP-Heptose as the ALPK1 ligand and activator of its kinase activity and TIFA protein a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
Go to US Patent