BDBM662008 N-(6-(2-(2-(((1r,4r)-4- aminocyclohexyl)amino)pyrimidin-5- yl)ethyl)-5-ethylpyridin-3-yl)-2- chlorobenzenesulfonamide::US11945784, Compound 16

SMILES CCc1cc(NS(=O)(=O)c2ccccc2Cl)cnc1CCc1cnc(NC2CC[C@H](N)CC2)nc1

InChI Key InChIKey=UQLCTRQDWCPBOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 662008   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
Cornell University

US Patent
LigandPNGBDBM662008(N-(6-(2-(2-(((1r,4r)-4- aminocyclohexyl)amino)pyri...)
Affinity DataIC50: 1nMAssay Description:In vitro FRET assay was performed to evaluate the ability of select compounds to inhibit IRE1, the results of which are summarized in Table 3. To per...More data for this Ligand-Target Pair
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Date in BDB:
6/17/2024
Entry Details
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