BDBM662007 N-(4-(2-(2-(((1r,4r)-4- aminocyclohexyl)amino)pyrimidin-5- yl)ethyl)-3-methoxyphenyl)-2- chlorobenzenesulfonamide::US11945784, Compound 15

SMILES COc1cc(NS(=O)(=O)c2ccccc2Cl)ccc1CCc1cnc(NC2CC[C@H](N)CC2)nc1

InChI Key InChIKey=FLELNAWSNAGJPT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 662007   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
Cornell University

US Patent
LigandPNGBDBM662007(N-(4-(2-(2-(((1r,4r)-4- aminocyclohexyl)amino)pyri...)
Affinity DataIC50: 1nMAssay Description:In vitro FRET assay was performed to evaluate the ability of select compounds to inhibit IRE1, the results of which are summarized in Table 3. To per...More data for this Ligand-Target Pair
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Date in BDB:
6/17/2024
Entry Details
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