BDBM661983 4-(6-(4-methyl-3,4-dihydro-2H- benzo[b][1,4]oxazin-7-yl)-3-((1- methylpyrrolidin-3-yl)methyl)-3H- imidazo[4,5-c]pyridin-7-yl)benzonitrile::US11944614, Compound 33

SMILES CN1CCC(Cn2cnc3c(-c4ccc(cc4)C#N)c(ncc23)-c2ccc3N(C)CCOc3c2)C1

InChI Key InChIKey=DLMUDTHKNJBVFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661983   

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandPNGBDBM661983(4-(6-(4-methyl-3,4-dihydro-2H- benzo[b][1,4]oxazin...)
Affinity DataIC50: 29.5nMAssay Description:Enzymatic activity was assessed using the AlphaLISA technology from Perkin Elmer Life Sciences (Waltham, Mass.). 2.5 μL of compound solution and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2024
Entry Details
Go to US Patent