BDBM66190 2-amino-6-(dicyanomethylene)-4-phenyl-1H-pyridine-3,5-dicarbonitrile::2-amino-6-(dicyanomethylidene)-4-phenyl-1H-pyridine-3,5-dicarbonitrile::2-azanyl-6-(dicyanomethylidene)-4-phenyl-1H-pyridine-3,5-dicarbonitrile::MLS001163959::SMR000539348::cid_910973

SMILES Nc1nc(C(C#N)C#N)c(C#N)c(-c2ccccc2)c1C#N

InChI Key InChIKey=YOKGAZCODZPKKU-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 66190   

TargetPhotoreceptor-specific nuclear receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM66190(cid_910973 | 2-azanyl-6-(dicyanomethylidene)-4-phe...)
Affinity DataIC50: 8.41E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66190(cid_910973 | 2-azanyl-6-(dicyanomethylidene)-4-phe...)
Affinity DataEC50:  1.92E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor corepressor 2 (TRAC-1)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM66190(cid_910973 | 2-azanyl-6-(dicyanomethylidene)-4-phe...)
Affinity DataIC50: 3.22E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetMajor prion protein(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM66190(cid_910973 | 2-azanyl-6-(dicyanomethylidene)-4-phe...)
Affinity DataIC50: 1.92E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetTyrosyl-DNA phosphodiesterase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM66190(cid_910973 | 2-azanyl-6-(dicyanomethylidene)-4-phe...)
Affinity DataIC50: 1.28E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay