BDBM661450 US20240101572, Example 59

SMILES COc1ccc(C2=NNC(=O)O[C@@]22CC[C@H](C[C@H](C)NC(=O)c3cc(Cl)no3)CC2)c(Br)c1

InChI Key InChIKey=OKFXDWUGKVMIEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661450   

TargetPhospholipase D1(Human)
Japan Tobacco

US Patent
LigandPNGBDBM661450(US20240101572, Example 59)
Affinity DataIC50: 10nMAssay Description:A DMSO or test substance solution (the DMSO final concentration: 5%) prepared by diluting DMSO or test substance with an Assay buffer (50 mmol/L HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetPhospholipase D2(Human)
Japan Tobacco

US Patent
LigandPNGBDBM661450(US20240101572, Example 59)
Affinity DataIC50: 10nMAssay Description:A DMSO or test substance solution (the DMSO final concentration: 5%) prepared by diluting DMSO or test substance with an Assay buffer (50 mmol/L HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent