BDBM661369 US20240101559, Compound I-8

SMILES CN1CCN(CC1)c1cc(Nc2nc3ccc(Oc4ccnc(NC(C)=O)c4)c4CCCn2c34)cc(c1)C(F)(F)F

InChI Key InChIKey=GMEQSJIEMFMVPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661369   

TargetTyrosine-protein kinase JAK2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM661369(US20240101559, Compound I-8)
Affinity DataIC50: 9.93E+3nMAssay Description:The JAK2 Z-Lyte biochemical assay was performed according to manufacturer's instructions (Life Technologies).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent