BDBM661268 US20240101559, Compound I-1

SMILES CCN1CCN(Cc2ccc(Nc3nc4ccc(Oc5ccnc(NC(C)=O)c5)c5CCCn3c45)cc2C(F)(F)F)CC1

InChI Key InChIKey=IFXGXPULMNAOIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661268   

TargetTyrosine-protein kinase JAK2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM661268(US20240101559, Compound I-1)
Affinity DataIC50: 820nMAssay Description:The JAK2 Z-Lyte biochemical assay was performed according to manufacturer's instructions (Life Technologies).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent