BDBM661183 3-(6-fluoropyridin-3-yl)-6-methyl-2-(4- (4-methyl-4H-1,2,4-triazol-3- yl)piperidin-1-yl)benzonitrile::US20240101544, Example 67

SMILES Cc1ccc(-c2ccc(F)nc2)c(N2CCC(CC2)c2nncn2C)c1C#N

InChI Key InChIKey=XETVHUDSLTVOAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661183   

TargetGlutaminyl-peptide cyclotransferase(Human)
TBA

US Patent
LigandPNGBDBM661183(US20240101544, Example 67 | 3-(6-fluoropyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCT (rhQPCT, R&D Systems) activity were determined using a biochemical fluorescent-based assay. QPCT acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

LigandPNGBDBM661183(US20240101544, Example 67 | 3-(6-fluoropyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCTL activity were determined using a biochemical fluorescent-based assay. QPCTL activity was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent