BDBM661081 (S)-4-(5-(N-((1-(1-(hydroxyamino)-3-(4-methoxyphenyl)-1-oxopropan-2-yl)-1H-1,2,3-triazol-4-yl)methyl)sulfamoyl)thiophen-2-yl)-N-methylbenzamide::US20240101542, Compound 28

SMILES CNC(=O)c1ccc(cc1)-c1ccc(s1)S(=O)(=O)NCc1cn(nn1)[C@@H](Cc1ccc(OC)cc1)C(=O)NO

InChI Key InChIKey=PSWHCOXIMQCCPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661081   

TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Human)
Universite De Lille

US Patent
LigandPNGBDBM661081(US20240101542, Compound 28 | (S)-4-(5-(N-((1-(1-(h...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetEndoplasmic reticulum aminopeptidase 2(Human)
Universite De Lille

US Patent
LigandPNGBDBM661081(US20240101542, Compound 28 | (S)-4-(5-(N-((1-(1-(h...)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent