BDBM661052 (E)-N-(2-fluoro-5-((4-(1-methyl-1H-pyrazol-4-yl)benzyl)amino)phenyl)-3-(furan-2-yl)acrylamide::US20240101538, Compound 107r

SMILES Cn1cc(cn1)-c1ccc(CNc2ccc(F)c(NC(=O)\C=C\c3ccco3)c2)cc1

InChI Key InChIKey=LPBCGQKTMKAFNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661052   

TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661052(US20240101538, Compound 107r | (E)-N-(2-fluoro-5-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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