BDBM661047 N-(5-((4-(1H-pyrazole-4-yl)benzyl)amino)-2-fluorophenyl)-3-(furan-2-yl)propanamide::US20240101538, Compound 2c

SMILES Fc1ccc(NCc2ccc(cc2)-c2cn[nH]c2)cc1NC(=O)CCc1ccco1

InChI Key InChIKey=WOVCGDDKYZBARE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661047   

TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661047(US20240101538, Compound 2c | N-(5-((4-(1H-pyrazole...)
Affinity DataIC50: 27.6nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
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