BDBM661044 N-(5-((4-(1H-Pyrazol-4-yl)benzyl)amino)-2-fluorophenyl)-3-phenylpropanamide::US20240101538, Compound 2a::US20240101538, Compound 95b

SMILES Fc1ccc(NCc2ccc(cc2)-c2cn[nH]c2)cc1NC(=O)CCc1ccccc1

InChI Key InChIKey=JLALVTVAANNEMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661044   

TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661044(US20240101538, Compound 95b | US20240101538, Compo...)
Affinity DataIC50: 7.90nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetAurora kinase A(Human)
Eberhard Karls Universitat Tubingen

US Patent
LigandPNGBDBM661044(US20240101538, Compound 95b | US20240101538, Compo...)
Affinity DataIC50: 6.90E+3nMAssay Description:To measure the effect of the compounds on the activity of AURKA, the IC50 of the compounds was determined with the ADP-Glo Kinase Assay (Promega, V91...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent