BDBM660975 1-(((1-((2-chloropyrimidin-5- yl)amino)isoquinolin-6- yl)oxy)methyl)cyclopropane- 1-carboxamide::US20240101531, Example 361

SMILES NC(=O)C1(COc2ccc3c(Nc4cnc(Cl)nc4)nccc3c2)CC1

InChI Key InChIKey=ZNOCISXYFIRDHV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660975   

TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660975(1-(((1-((2-chloropyrimidin-5- yl)amino)isoquinolin...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent