BDBM660962 US20240101531, Example 348::US20240101531, Example 358::cis-3-((1-((2-chloropyrimidin- 5-yl)amino)isoquinolin-6- yl)oxy)cyclohexan-1-ol

SMILES O[C@@H]1CCC[C@@H](C1)Oc1ccc2c(Nc3cnc(Cl)nc3)nccc2c1

InChI Key InChIKey=HUMAFDZVMHMRJH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 660962   

TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660962(US20240101531, Example 348 | US20240101531, Exampl...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660962(US20240101531, Example 348 | US20240101531, Exampl...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent